{"id":143949,"date":"2025-01-09T12:37:41","date_gmt":"2025-01-09T11:37:41","guid":{"rendered":"https:\/\/www.startupbusiness.it\/genenta-strengthens-collaboration-with-agc-on-cell-therapies\/143949\/"},"modified":"2025-01-09T12:40:30","modified_gmt":"2025-01-09T11:40:30","slug":"genenta-strengthens-collaboration-with-agc-on-cell-therapies","status":"publish","type":"post","link":"https:\/\/www.startupbusiness.it\/en\/genenta-strengthens-collaboration-with-agc-on-cell-therapies\/143949\/","title":{"rendered":"Genenta strengthens collaboration with AGC on cell therapies"},"content":{"rendered":"\n<p>Genenta Science, a Nasdaq-listed Italian scaleup operating in the field of immuno-oncology through the production of cell therapies, announces that it has strengthened its partnership with AGC Biologics, a global contract development and manufacturing organisation (CDMO). <strong>The evolution of the agreement introduces an exclusive GMP suite at AGC Biologics&#8217; Cells and Genes Centre of Excellence in Milan, Italy, dedicated to the production of Genenta&#8217;s cell therapy products, ensuring compliance with cGMP standards<\/strong>. This strategic move enhances Genenta&#8217;s manufacturing capabilities, potentially improving the efficiency and reliability of its production processes. <\/p>\n\n<p>The recently approved phase 1\/2a study in metastatic renal cell cancer (mRCC) started in the fourth quarter of 2024 and Genenta expects to treat six patients by the first half of 2025, while the glioblastoma multiforme (GBM) study continues to progress. In total, Genenta plans to produce 27 autologous drug products in 2025. <\/p>\n\n<p><strong>&#8220;Our strengthened partnership with AGC Biologics represents our continued commitment to patients participating in our GBM and mRCC trials,&#8221; Pierluigi Paracchi, CEO and co-founder of Genenta (pictured), said in a note. <\/strong>&#8220;This increased capacity allows us to treat more patients and further validate our therapeutic approach, bringing us closer to our vision of transforming cancer treatment through cell therapies.<\/p>\n\n<p><strong>Luigi Naldini, co-founder of Genenta, adds: &#8216;Our recent preclinical and clinical studies underline Temferon&#8217;s unique potential to reprogram the tumour microenvironment by inhibiting myeloid cell-induced immune suppression and promoting T-cell responses. <\/strong>This approach not only increases the tumour&#8217;s treatment potential, but also its ability to reduce the number of tumour cells and increases the potential efficacy of Temferon as monotherapy, also suggesting promising synergies when combined with various immunotherapeutic strategies, including immune checkpoint inhibitors and CAR-T cell therapies. These results provide a solid basis for the advancement of therapeutic strategies targeting solid tumours and bring us closer to the opening of new anti-cancer treatments&#8217;. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Italian scaleup will be able to treat more cancer patients thanks to this new 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tumori"},"2048x2048":{"src":"https:\/\/www.startupbusiness.it\/wp-content\/uploads\/2025\/01\/paracchi.webp","width":1346,"height":1020,"crop":false,"srcset":false,"alt":"terapie cellulari tumori"}},"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Genenta strengthens collaboration with AGC on cell therapies<\/title>\n<meta name=\"description\" content=\"The Italian scaleup will be able to treat more cancer patients thanks to this new agreement\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.startupbusiness.it\/en\/genenta-strengthens-collaboration-with-agc-on-cell-therapies\/143949\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Genenta strengthens collaboration with AGC on cell therapies\" \/>\n<meta property=\"og:description\" content=\"The Italian scaleup will be able to treat more cancer patients thanks to this new agreement\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.startupbusiness.it\/en\/genenta-strengthens-collaboration-with-agc-on-cell-therapies\/143949\/\" \/>\n<meta property=\"og:site_name\" content=\"Startupbusiness.it\" \/>\n<meta property=\"article:published_time\" content=\"2025-01-09T11:37:41+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-01-09T11:40:30+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.startupbusiness.it\/wp-content\/uploads\/2025\/01\/paracchi.webp\" \/>\n\t<meta property=\"og:image:width\" content=\"1346\" \/>\n\t<meta property=\"og:image:height\" content=\"1020\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/webp\" \/>\n<meta name=\"author\" content=\"Emil Abirascid\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta 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Co-fondatore di Designtech, l\u2019hub di innovazione che avvicina il mondo del design con quello della tecnologia. Advisor di Austrian Business Agency, Emil Banca, Fondazione Symbola, Fondazione Quadrans. Partecipa regolarmente a incontri, convegni, conferenze dedicate all\u2019ecosistema dell\u2019innovazione. E\u2019 stato co-organizzatore degli Italian Innovation Day and Series che si sono svolti dal dal 2016 al 2020 nelle citt\u00e0 di Tokyo in Giappone, Melbourne, Adelaide, Perth, Canberra in Australia e Singapore e co-organizzatore dell\u2019Italy India Innovation Day di AIICP 2021 e 2022. Ha curato il volume \u2018L\u2019innovazione che non ti aspetti. 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